U.K.-based Perpetual Atomics and U.S.-based QSA Global claim to have achieved a major step forward in processing americium dioxide to fuel radioisotope power systems used in space missions. Using an industrially scalable process, the companies said they have turned americium into stable, large-scale ceramic pellets that can be directly integrated into sealed sources for radioisotope power systems, including radioisotope heater units (RHUs) and radioisotope thermoelectric generators (RTGs).

QSA Global, a provider of radioisotope products, and Niowave, a Michigan-based producer of medical radioisotopes, announced that the companies will codevelop a scalable radium purification process using Niowave’s radium-226 processing technology to meet the demand for actinium-225, an alpha-emitter used in the treatment of cancer. According to the companies, the strategic partnership marks a significant advancement in the field of radiopharmaceutical technology, enhancing the supply chain for critical radioisotopes, including Ac-225.

Niowave uses a closed-loop cycle to produce high-purity Ac-225 and other alpha emitters from Ra-226 using a superconducting electron linear accelerator. According to the company’s website, the electron beam impinges on a photon converter to irradiate the Ra-226, inducing a photon-neutron reaction to Ra-225, which decays to Ac-225.

The Department of Energy Isotope Program and QSA Global, a Burlington, Mass.–based manufacturer of sealed radioisotope sources, agreed to a joint product development project to initiate domestic production of iridium-192, which is used in industrial gamma ray radiography.